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- David M. Good, Petra Zürbig, +43 authors Philippe Schmitt-Kopplin
- Molecular & cellular proteomics : MCP
- 2010
Because of its availability, ease of collection, and correlation with physiology and pathology, urine is an attractive source for clinical proteomics/peptidomics. However, the lack of comparable data… (More)
- Maciej T Malecki, Ulupi S. Jhala, +7 authors Andrzej S Krolewski
- Nature Genetics
- 1999
The helix-loop-helix (HLH) protein NEUROD1 (also known as BETA2) functions as a regulatory switch for endocrine pancreatic development. In mice homozygous for a targeted disruption of Neurod,… (More)
- Bruce A Perkins, Linda H. Ficociello, +4 authors Andrzej S Krolewski
- Journal of the American Society of Nephrology…
- 2007
This study aimed to establish the time of initiation and the determinants of renal function decline in type 1 diabetes. Until now, such decline has been assumed to be a late-occurring event… (More)
- James H. Warram, G Gearin, L M Laffel, Andrzej S Krolewski
- Journal of the American Society of Nephrology…
- 1996
The objective of this study was to determine the prevalence of stages of diabetic nephropathy, defined by the albumin/creatinine ratio (AC ratio) in repeated measurements in random urine samples.… (More)
- Monika A Niewczas, Tomohito Gohda, +9 authors Andrzej S Krolewski
- Journal of the American Society of Nephrology…
- 2012
Levels of proinflammatory cytokines associate with risk for developing type 2 diabetes but whether chronic inflammation contributes to the development of diabetic complications, such as ESRD, is… (More)
- Joann E. Manson, Eric B. Rimm, +6 authors Frank E. Speizer
- The Lancet
- 1991
The potential role of physical activity in the primary prevention of non-insulin-dependent diabetes mellitus (NIDDM) is largely unknown. We examined the association between regular vigorous exercise… (More)
- Patricia W. Mueller, John J. Rogus, +9 authors James H. Warram
- Journal of the American Society of Nephrology…
- 2006
The Genetics of Kidneys in Diabetes (GoKinD) study is an initiative that aims to identify genes that are involved in diabetic nephropathy. A large number of individuals with type 1 diabetes were… (More)
- Marcus G. Pezzolesi, G David Poznik, +25 authors Andrzej S Krolewski
- Diabetes
- 2009
OBJECTIVE
Despite extensive evidence for genetic susceptibility to diabetic nephropathy, the identification of susceptibility genes and their variants has had limited success. To search for genes… (More)
- James H. Warram, Blaise C Martin, Andrzej S Krolewski, Jens-Hendrik Soeldner, C Ronald Kahn
- Annals of internal medicine
- 1990
OBJECTIVE
To determine whether insulin resistance or insulin deficiency is primary in the pathogenesis of type II diabetes.
DESIGN
Cohort analytic study of persons with normal glucose tolerance but… (More)
- Andrzej S Krolewski, James H. Warram, A R Christlieb, Edward J. Busick, C Ronald Kahn
- The American journal of medicine
- 1985
Events in the natural history of diabetic nephropathy (including the onset of persistent proteinuria and end-stage renal failure) were studied in a cohort of 292 patients with juvenile-onset type I… (More)