Andrzej K. Brodzik

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—Alignment of DNA segments containing repetitive nucleotide base patterns is an important task in several genomics applications, including DNA sequencing, DNA fingerprinting, pathogen detection, and gene finding. One of the most efficient procedures used for this task is the cross correlation method. The main computations of the procedure are the discrete(More)
MOTIVATION One of the main tasks of DNA sequence analysis is identification of repetitive patterns. DNA symbol repetitions play a key role in a number of applications, including prediction of gene and exon locations, identification of diseases, reconstruction of human evolutionary history and DNA forensics. RESULTS A new approach towards identification of(More)
In this work we consider the problem of global DNA sequence alignment. One of the best known and most efficient computational techniques used for this task is the cross-correlation method. We compare efficacy of evaluating periodic DNA sequence mis-alignment using the standard magnitude-and-phase cross-correlation technique with the lesser known phase-only(More)
In this work we focus on the relationship between the Dempster-Shafer (DS) and Bayesian evidence accumulation. While it is accepted that the DS theory is, in a certain sense, a generalization of the probability theory, the approaches vary in several important respects, including the treatment of uncertain information and the way the evidence is combined,(More)