Mutations at the natural resistance–associated macrophage protein 1 (Nramp1) locus cause susceptibility to infection with antigenically unrelated intracellular pathogens. Nramp1 codes for an integral membrane protein expressed in the lysosomal compartment of macrophages, and is recruited to the membrane of phagosomes soon after the completion of… (More)
" The problem of understanding of intelligence is said to be the greatest problem in science today and " the " problem for this century – as deciphering the genetic code was for the second half of the latest one. Arguably, the problem of learning represents a gateway to understanding intelligence in brains and machines, to discovering how the human brain… (More)
Developing methods for approximation of compound concepts expressing the result of perception belongs to the main challenges of Perception Based Computing (PBC) . The perceived concepts are expressed in natural language. We discuss the rough-granular approach to approximation of such concepts from sensory data and domain knowledge. This additional… (More)
We discus the Wisdom Granular Computing (WGC) as a basic methodology for Perception Based Computing (PBC). By wisdom, we understand an adaptive ability to make judgements correctly to a satisfactory degree (in particular, correct decisions) having in mind real-life constraints. We propose Rough-Granular Computing (RGC) as the basis for WGC.
We discuss how to support commanders at the fire ground. We present a risk management framework for modelling the fire phenomena and for communicating with firefighters. We claim that appropriate derivation, selection and representation of information is the crucial aspect of decision support, as it may improve the commander's perception.