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Mutations at the natural resistance–associated macrophage protein 1 (Nramp1) locus cause susceptibility to infection with antigenically unrelated intracellular pathogens. Nramp1 codes for an integral membrane protein expressed in the lysosomal compartment of macrophages, and is recruited to the membrane of phagosomes soon after the completion of(More)
We discuss how to support commanders at the fire ground. We present a risk management framework for modelling the fire phenomena and for communicating with firefighters. We claim that appropriate derivation, selection and representation of information is the crucial aspect of decision support, as it may improve the commander's perception.