Andrius Sakalauskas

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BACKGROUND Essential tremor (ET) and Parkinson's disease (PD) are considered distinct disorders. The aim of the study was to look for a link or any distinguishing features by transcranial sonography (TCS), together with the clinical examination findings in a group of patients with overlapping phenotype of ET and PD (ET-PD). METHODS A prospective(More)
This paper presents a novel and rapid method developed for semi-automated segmentation of the mid-brain region in B-mode trans-cranial ultrasound (TCS) images. TCS is a relatively new neuroimaging tool having promising application in early diagnosis of Parkinson's disease. The quality of TCS images is much lower compared with the ultrasound images obtained(More)
BACKGROUND Hyperechogenicity of the substantia nigra (SN+), detected by transcranial sonography (TCS), was reported as a characteristic finding in Parkinson's disease (PD), with high diagnostic accuracy values, when compared mainly to healthy controls or essential tremor (ET) group. However, some data is accumulating that the SN + could be detected in other(More)
Images captured during routine clinical transcranial sonography (TCS) examination are of a low resolution, so can be confusing for diagnostic evaluations. Manual segmentation of brain structures (areas of the midbrain and substantia nigra (SN)) that are of special interest cause inter-observer and intra-observer variability, thus restricting the reliability(More)
Parkinson disease (PD) is one of the most common neurodegenerative disorders. The aim of this study is to review the main problems of transcranial echoscopy (TCE) by the pilot clinical investigations and to analyze opportunities and possible technical solutions for improvement of diagnostic of Parkinson disease using ultrasound applications. TCE is(More)
Long-term periodic monitoring of cardiovascular function in unobtrusive way has been a challenge in sensor research lately. This work presents the investigation of the method for pulse arrival time (PAT) estimation using body composition scales. It employs the electrocardiogram and the impedance plethysmogram (IPG) which are recorded from palm and plantar(More)
Diagnostic value of ultrasonic B-mode imaging is dependent on interpretation and competence of physician, because only information about single section of tissues volume is used for evaluation. 3D sonography systems for abdominal diagnostics are available, but such systems are not yet available in transcranial sonography and etc. One of possibilities to(More)
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