Andriani Daskalaki

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MiRNAs are discussed as diagnostic and therapeutic molecules. However, effective miRNA drug treatments with miRNAs are, so far, hampered by the complexity of the miRNA networks. To identify potential miRNA drugs in colorectal cancer, we profiled miRNA and mRNA expression in matching normal, tumor and metastasis tissues of eight patients by Illumina(More)
Cancer is known to be a complex disease and its therapy is difficult. Much information is available on molecules and pathways involved in cancer onset and progression and this data provides a valuable resource for the development of predictive computer models that can help to identify new potential drug targets or to improve therapies. Modeling cancer(More)
Non-alcoholic fatty liver disease comprises a broad spectrum of disease states ranging from simple steatosis to non-alcoholic steatohepatitis. As a result of increases in the prevalences of obesity, insulin resistance, and hyperlipidemia, the number of people with hepatic steatosis continues to increase. Differences in susceptibility to steatohepatitis and(More)
Non-alcoholic fatty liver disease (NAFLD) is a consequence of sedentary life style and high fat diets with an estimated prevalence of about 30% in western countries. It is associated with insulin resistance, obesity, glucose intolerance and drug toxicity. Additionally, polymorphisms within, e.g., APOC3, PNPLA3, NCAN, TM6SF2 and PPP1R3B, correlate with(More)
A Collection of 14 Scholarly Titles Technological advances over the last several decades have dramatically changed the face of medicine, making diagnosis and treatment faster and safer for patients. The areas of nursing informatics and clinical technologies are no exception and practitioners in these areas must stay up-to-date on the latest technological(More)
AbstrAct Computer-based learning has been developed for the beginning medical student and the experienced practitioner, for the lay person and the medical expert. There are many advantages to online and computer-based learning when compared to traditional face-to-face courses and lectures. Information technologies are providing new opportunities for linking(More)