Andrey Manov

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A case is presented of a 28-year-old man with Hand-Schüller-Christian's disease whose initial manifestations were skull bones lesions and a diffuse interstitial fibrosis. Three years later the patient developed diabetes insipidus without changes in the hypothalamic-hypophysial region on computed tomography. Some features of the clinical picture are(More)
A case of a woman with Itsenko [correction of Icenko]-Cushing's disease and a rare complication--necrosis of the fingers of the left hand--is presented. Besides the known factors of hypercorticism injuring the vascular wall, cryoglobulinemia was found in the patient. It is probably secondary in this disease and points out the complicated changes in the(More)
The stimulation test--TRH test was carried out with the Bulgarian drug "Protilerin" in 63 patients (Basedow's disease--53 patients, basedoid goiter--5 patients, infiltrative ophthalmopathy--5 patients) and in 20 healthy controls. The healthy controls showed normal reaction to the stimulation. All patients with hyperthyroidism showed a suppressed response to(More)
Human insulin was applied to three insulin resistant diabetic patients with moderate insulin needs of 1.9 U/kg body mass/24 hours. The mean level of the insulin antibodies was 61%. In all three patients biostator control was carried out before beginning the treatment with human insulin. After an 8 month treatment a satisfactory compensation of diabetes was(More)
The test stripes Visidex for visual evaluation of glycemia were tested clinically. The results were compared with a reference laboratory method for blood sugar measurement. A correlation coefficient of r = 0.971 with 74% coincidence in the same glycemic interval was found. The test stripes are suitable for blood sugar self-control in domestic conditions.
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