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The paper is devoted to membrane mechanisms of sodium influx from the extracellular medium to the cytoplasm in nonexcitable cells. With the use of patch clamp technique, the activity of non-voltage-gated ionic channels in plasma membrane of human leukemia K562 cells was examined. We have identified two types of Na-permeable channels characterized by unitary(More)
The channel proteins so far known are transmembrane oligomers arranged in a manner that the polar residues are lining the central ion-conducting hydrophilic pore. In the last decade, electrophysiology and molecular biology studies revealed the principal similarity in the functional properties and membrane topology within a large family of sodium-conducting(More)
Post-gastrectomy and post-resection conditions are occurring more frequently due to the growing number of radical operations carried out for stomach cancer. The available procedures for restoring the natural continuity of the gastrointestinal tract are either too sophisticated or ineffective. A new technique of primary jejunogastroplasty following subtotal(More)
Morphological changes in the mouse thymus in the experimental autoimmune hemolytic anemia were correlated with the results of the study of the immune status. The epithelial component of the thymus was more involved in the response to the experimental autoimmune hemolytic anemia during the whole experiment; this allows one to assume that just this component(More)
KVEST – Kernel VErification and Specification Technology – is based on automated test generation from formal specifications. The technology was developed under a contract with Nortel Networks and is based on experience gained in academic research [1]. By 2000 the methodology and the toolset have been applied in 6 industrial projects dealing with the(More)
The immediate and long-term results of 500 reconstructive operations on the aorticfemoral segment using a miniaccess were analyzed. 443 patients suffered from the obliterative atherosclerosis and 57 were operated on the infrarenal aortic aneurism. The size of the surgical access was 5-12 sm (418 through laparotomy, 82 through the retroperitoneal access).(More)