Andrey G. Nikiforov

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The metabolism of NAD has emerged as a key regulator of cellular and organismal homeostasis. Being a major component of both bioenergetic and signaling pathways, the molecule is ideally suited to regulate metabolism and major cellular events. In humans, NAD is synthesized from vitamin B3 precursors, most prominently from nicotinamide, which is the(More)
Dualization is a key discrete enumeration problem. It is not known whether or not this problem is polynomial-time solvable. Asymptotically optimal dualiza-tion algorithms are the fastest among the known dualization algorithms, which is supported by new experiments with various data described in this paper. A theoretical justification of the efficiency of(More)
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