Andrey Chernyaev

Learn More
We studied the content of resident myocardial stem cells, cardiomyocyte precursors, in myocardial biopsy specimens from the right ventricular outfl ow tract of patients of the fi rst two years of life with tetralogy of Fallot. Myocardial resident stem cells were detected by the method of confocal immunohistochemistry using antibodies to c-kit and sarcomeric(More)
Interventricular septum myocardium was studied in 40 patients with obstructive hypertrophic cardiomyopathy. Immunohistochemical assay revealed c-kit-positive resident cardiac stem cells in 82.5% patients. The content of the connective tissue and myofi brillar disarray zones and the degree of cardiomyocyte hypertrophy and myolysis were determined. In 30%(More)
BACKGROUND The diagnosis of pulmonary alveolar proteinosis (PAP) is based on computed tomography, histology, and antibodies to granulocyte-macrophage colony-stimulating factor. The role of a novel technique for imaging cells and elastin during endoscopy, probe-based confocal laser endomicroscopy (pCLE), has not yet been investigated in PAP patients. The aim(More)
We have performed cytophotometry for DNA in isolated myocytes of the left ventricle from 16 men, aged 19-39 years, who died from various non-cardiac or pulmonary causes. The mean ploidy of myocytes varied from 3.2-3.9 c to 6.6-7.3 c in different layers of the anterior wall of the left ventricle (where c is the haploid DNA content measured by cytophotometry(More)
The paper provides a clinical note. A 45-year-old patient suffered from severe primary emphysema and underwent bilateral lung transplantation. A year after surgery, exercise dyspnea again appeared in the patient. Lung computed tomography revealed multiple rounded soft tissue masses; thoracoscopic biopsy and further histological examination proved the(More)
Of all reconstructive operations on the bronchi 5-10% are undertaken on patients with cancer and 70% on patients with benign tumors [I, 5, 7, Ii, 12]; suture failure, and granulations and cicatricial stenosis of the anastomoses develop in 5-10% of patients [4, 8-10]. As a rule, interrupted sutures passing through all layers of the bronchial wall are used in(More)
Experiments were carried out on 210 male albino rats receiving cadmium chloride solution by gastric tube in a dose of 2.5 mg/100 g body weight (0.25 LD), five times a week for 12 weeks, followed by a recovery period of 9 weeks. Every week the blood pressure (BP) was measured in the caudal artery, using a modified Korotkov's method [2]. Additionally, in the(More)
Morphological alterations of microvessels in bronchial mucosa and blood capillaries of alveolar septa during endobronchitis were examined in workers employed at a plutonium plant and not employed residents (Zheleznogorsk, Krasnoyarsk Region). Alterative, destructive, and dysadaptive changes in pulmonary vessels of workers were paralleled by developing(More)
I. A. V. Val'dman, in: Experimental Neurophysiology of Emotions [in Russian], Leningrad (1972), p. 142. 2. A. V. Val'dman, M. M. Kozlovskaya, and O. S, Medvedev, Pharmacologic Regulation of Emotional Stress [in Russian], Moscow (1979). 3. Ya. I. Veksler, N, G. Atabegova, M. S. Arbukhanova, et al., in: Current Problems in Stress [in Russian], Kishinev(More)
In rats with hypertension modeled by the one kidney-one clamp method, constrictory responses of the isolated caudal artery to norepinephrine differed under various perfusion conditions. Vascular reactions in hypertensive rats were more potent at a constant flow rate, and less potent at a constant pressure compared to those in normotensive rats. Previous(More)
  • 1