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Transforming growth factor-beta1 (TGF-beta) can be tumor suppressive, but it can also enhance tumor progression by stimulating the complex process of epithelial-to-mesenchymal transdifferentiaion (EMT). The signaling pathway(s) that regulate EMT in response to TGF-beta are not well understood. We demonstrate the acquisition of a fibroblastoid morphology,(More)
The number and location of pseudouridine residues in Escherichia coli 16S ribosomal RNA has been determined by a combination of direct and indirect methods. Only one residue was found, at position 516. This site is at the 5'-end of one of the three most highly conserved long sequences of this RNA molecule. A number of experimental findings have strongly(More)
The electrical properties of high-resistivity zinc oxide (ZnO) bulk and epi-samples are strongly influenced by the sample ambient. Bulk samples that are highly resistive in ambient air can be reversibly transformed into a high conducting state under vacuum. As an explanation we suggest a conducting electron channel at the ZnO surface. Under vacuum this(More)
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