Andrew U Luescher

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This article discusses the presenting signs, diagnosis, and differential diagnosis of compulsive disorder. Problems with the diagnosis and heterogeneity of the condition are discussed. Likely causes, development, and pathophysiology of the condition form the basis for the clinical approach to the treatment of the condition. Treatment includes environmental(More)
Canine separation anxiety is a common behavioral problem presented to veterinarians. Associated behaviors are distressing to both dog and owner, have the potential to disrupt the human-companion animal bond, and may lead to euthanasia. The results of this study demonstrate the clinical efficacy and safety of Reconcile (fluoxetine, 1 to 2 mg/kg/day [0.45 to(More)
OBJECTIVE To evaluate efficacy of fluoxetine hydrochloride for treatment of compulsive disorders in dogs. DESIGN Randomized, controlled clinical trial. ANIMALS 63 dogs with compulsive disorders. PROCEDURES The diagnosis was confirmed on the basis of analysis of videotapes of the dogs' behavior by 3 veterinary behaviorists, results of physical(More)
OBJECTIVE To determine bioavailability, pharmacokinetics, and safety for transdermal (TD) and oral administration of fluoxetine hydrochloride to healthy cats. ANIMALS 12 healthy mixed-breed sexually intact 1- to 4-year-old purpose-bred cats. PROCEDURE A single-dose pharmacokinetic study involving 3 groups of 4 cats each was conducted in parallel.(More)
The positron emission tomography (PET) imaging technique, which is utilized in human behavior and psychiatric disorder research, was performed on the brains of clinically normal mixed breed dogs, 3 hound-type (long floppy ears) mixed breed dogs and 3 non-hound retriever-type mixed breed dogs. Glucose metabolism was obtained with F-18 fluorodeoxyglucose(More)
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