Andrew S O'connor

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BACKGROUND A low rate of blood pressure control has been reported in patients with chronic kidney disease (CKD). These data were derived from population-based samples with a low rate of CKD awareness. STUDY DESIGN Cross-sectional. SETTING & PARTICIPANTS Data from the baseline visit of the Chronic Renal Insufficiency Cohort (CRIC) Study (n = 3,612) were(More)
BACKGROUND Medicare's reimbursement system was changed in January 2004 to encourage more frequent visits between dialysis patients and nephrologists. We sought to determine the impact of this policy change on patient-nephrologist visits, quality of care, and health-related quality of life. METHODS We examined visits and outcomes for 2,043 patients at 12(More)
The objective of the study was to determine whether chronic kidney disease (CKD) is as important a risk as either diabetes mellitus (DM) or previous myocardial infarction (MI). CKD and DM are important coronary artery disease risk factors. We hypothesized that the risk of cardiovascular mortality in elderly patients with CKD is equivalent to that for(More)
BACKGROUND ROP-Os/+ mice are born with oligosyndactyly and oligonephronia and develop renal dysfunction, which includes renal tubular epithelial cell (RTC) Fas-dependent apoptosis and tubular atrophy. MRL/lpr mice harbor a Fas-inactivating mutation and develop glomerulonephritis, whereas mice expressing lpr on a C3H background demonstrate no renal(More)
Clinical performance measures, including dialysis dose, hemoglobin, albumin, and vascular access, are the focus of monitoring and quality improvement activities. However, little is known about the implications of clinical performance measures for hospital utilization and health care costs. We obtained clinical performance measures and hospitalization(More)
Sarcoidosis is a chronic granulomatous inflammatory disease that may affect extrapulmonary organs including the kidneys and the gastrointestinal tract (1). The most common renal complication from sarcoidosis is hypercalciuria, which may induce nephrocalcinosis and/or nephrolithiasis (2). Chronic interstitial nephritis with noncaseating granulomas in the(More)
BACKGROUND The amount of hemodialysis that patients receive is an independent predictor of mortality. However, the relative predictive ability of four common measures of dialysis dose (urea reduction ratio, single-pool Kt/V, double-pool Kt/V, and urea index) is unclear. METHODS Using The Renal Network Data System, we identified 14,810 incident(More)
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