Andrew Paul

Publications61
h-index14
Citations591
Highly Influential Citations33
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • M. Karin
  • 805 Publications, 219,845 Citations
  • R. Plevin
  • 151 Publications, 6,556 Citations
  • D. McMillan
  • 574 Publications, 22,231 Citations
  • J. Edwards
  • 131 Publications, 2,541 Citations
  • Publications
  • Influence
Inhibition of Lipopolysaccharide-Induced Macrophage IL-12 Production by Leishmania mexicana Amastigotes: The Role of Cysteine Peptidases and the NF-κB Signaling Pathway1
Infection with lesion-derived Leishmania mexicana amastigotes inhibited LPS-induced IL-12 production by mouse bone marrow-derived macrophages. This effect was associated with expression of cysteine… Expand
  • 160
  • 9
Inhibitory kappa B kinases as targets for pharmacological regulation
The inhibitory kappa B kinases (IKKs) are well recognized as key regulators of the nuclear factor kappa B (NF‐κB) cascade and as such represent a point of convergence for many extracellular agents… Expand
  • 78
  • 6
Differential Modulation of TLR3- and TLR4-Mediated Dendritic Cell Maturation and Function by Progesterone
The role of progesterone in modulating dendritic cell (DC) function following stimulation of different TLRs is relatively unknown. We compared the ability of progesterone to modulate murine bone… Expand
  • 49
  • 4
Essential Role for Verotoxin in Sustained Stress-Activated Protein Kinase and Nuclear Factor Kappa B Signaling, Stimulated by Escherichia coli O157:H7 in Vero Cells
ABSTRACT The effects of Escherichia coli O157:H7 (strains E30480 and PM601) and the associated verotoxins (VTs), VT1 and VT2, on stress-activated protein kinase and nuclear factor kappa B (NF-κB)… Expand
  • 18
  • 2
Enhancement of lipopolysaccharide‐stimulated JNK activity in rat aortic smooth muscle cells by pharmacological and adenovirus‐mediated inhibition of inhibitory kappa B kinase signalling
In rat aortic smooth muscle cells (RASMCs), the putative nuclear factor kappa B (NFκB) inhibitor Pyrrolidine dithiocarbamate (PDTC) was found to inhibit lipopolysaccharide (LPS)‐stimulated NFκB… Expand
  • 11
  • 2
Switching leukemia cell phenotype between life and death.
Divergent life or death responses of a cell can be controlled by a single cytokine (tumor necrosis factor alpha, TNF) via the signaling pathways that respond to activation of its two receptors (TNFR1… Expand
  • 35
  • 1
P2X7 subunit-like immunoreactivity in the nucleus of visceral smooth muscle cells of the guinea pig
P2X receptors are adenosine 5'-triphosphate (ATP)-gated cation-selective channels. Seven cloned subunits (P2X(1-7)) are found in the plasma membrane of many cells in the brain and periphery.… Expand
  • 18
  • 1
Cell signalling pathways involved in the regulation of vascular smooth muscle contraction and relaxation
  • 7
  • 1
Surgical optimization and characterization of a minimally invasive aortic banding procedure to induce cardiac hypertrophy in mice
Left ventricular pressure overload in response to aortic banding is an invaluable model for studying progression of cardiac hypertrophy and transition to heart failure. Traditional aortic banding has… Expand
  • 26
  • 1
Selective inhibition of inhibitory kappa B kinase‐β abrogates induction of nitric oxide synthase in lipopolysaccharide‐stimulated rat aortic smooth muscle cells
In this study, we utilised a number of adenoviral constructs in order to examine the role of intermediates of the NF‐κB pathway in the regulation of inducible nitric oxide synthase (iNOS) induction… Expand
  • 15
  • 1