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OBJECTIVE To evaluate the anatomical and visual outcomes of patients treated with ocriplasmin for the treatment of symptomatic vitreomacular adhesion (sVMA), including vitreomacular traction syndrome and macular holes. DESIGN Retrospective, interventional, single centre, case series. PARTICIPANTS Patients with sVMA. INTERVENTION Patients were treated(More)
AIM To evaluate efficacy and safety of intravitreal aflibercept injection (IAI) in subjects who were previously treated with ranibizumab and/or bevacizumab for active exudative age-related macular degeneration (AMD). METHODS Patients (n=26) were enrolled in a 12-month prospective, interventional, single arm, investigator-initiated study with planned(More)
OBJECTIVE To estimate the 9-year incidence of diabetic retinopathy (DR) in a population with the same ancestry as African Americans. METHODS Participants with diabetes mellitus and gradable photographs at the 9-year examination were evaluated (n = 436). The incidences of minimum/moderate/severe DR, clinically significant macular edema (CSME), and(More)
Retinoblastoma is the most common primary ocular malignancy of young children, with an incidence of 1:17000 to 1:34000 new births. Reti-noblastoma is bilateral in about 30% of cases. 1 Although new modalities offer an enhanced chance of eye salvage , in bilateral disease, management often leads to enucleation of the more-involved eye, with more conservative(More)
A 45-year-old man with extensive myelinated retinal nerve fibers had an attack of anterior ischemic optic neuropathy. Serial fundus photographs documented the loss of myelin. Visual acuity in the affected eye decreased to 6/90 (20/300) and color perception was markedly reduced. The visual fields in the affected eye showed dense superior and inferior arcuate(More)
Uveal melanoma 1 is the most common primary ocular malignancy in whites and represents 70% of all primary ocular malignancies. In patients with metastatic uveal melanoma, the prognosis for those with initial me-tastasis to the liver is particularly poor. The median survival of patients who first develop liver metastasis from uveal melanoma is 5 to 7 months,(More)
I n all fields of medicine, many investigators choose to present their research at scientific meetings before publication. In ophthalmology, a variety of organizations provide venues for such presentations, for example, at the annual meetings of the Association for Research in Vision and Ophthalmology or the American Academy of Ophthalmology. Presentations(More)
OBJECTIVE To determine whether access to color fundus photographs from a patient's previous visit would alter the recommendations rendered to a cohort with diabetic retinopathy. PATIENTS AND METHODS One hundred sixty patients with diabetic retinopathy returning for a follow-up visit and who had color fundus photographs obtained at a previous visit were(More)
SUMMARY STATEMENT In subjects with active exudative age-related macular degeneration, treating with a fixed intravitreal aflibercept injection dosing regimen for 12 months demonstrated improved anatomic and vision endpoints from baseline. PURPOSE Switching therapies in neovascular age-related macular degeneration (AMD) may offer an advantage for some(More)