Andrew P. Cox

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Pachycephalosaurian dinosaurs have dorsally thickened crania and uniquely shaped frontoparietal domes in some genera, suggested as evidence for head-or flank-butting behavior. Trabeculae thought to have resisted impact compression are present as only one histological zone of some pachycephalosaur domes, and are surrounded superficially or replaced by thick(More)
Active case detection through mass community screening is a major control strategy against human African trypanosomiasis (HAT, sleeping sickness) caused by T. brucei gambiense. However, its impact can be limited by incomplete attendance at screening sessions (screening coverage) and diagnostic inaccuracy. We developed a model-based approach to estimate the(More)
BACKGROUND There is urgent need for effective HIV prevention methods that women can initiate. The CAPRISA 004 trial showed that a tenofovir-based vaginal microbicide had significant impact on HIV incidence among women. This study uses the trial findings to estimate the population-level impact of the gel on HIV and HSV-2 transmission, and price thresholds at(More)
BACKGROUND In China, female sex workers (FSWs) are at high risk of syphilis infection, but are hard to reach for interventions. Point-of-care testing introduces opportunities for expanding syphilis control measures. Modelling is used to estimate the impact of using rapid tests to screen FSWs for syphilis. In other settings, modelling has predicted large(More)
OBJECTIVE To describe a framework for the initiation and ongoing monitoring of patients on clozapine, and detail support materials that can be used in clinical settings, including general practice, to support this process. CONCLUSIONS A framework is described. Clozapine has a special place in the management of treatment-resistant schizophrenia. However,(More)
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