Andrew O'Connor

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BACKGROUND AND PURPOSE Delayed cerebral ischemia (DCI) is an important cause of poor outcome after aneurysmal subarachnoid hemorrhage (SAH). Trials of magnesium treatment starting <4 days after symptom onset found no effect on poor outcome or DCI in SAH. Earlier installment of treatment might be more effective, but individual trials had not enough power for(More)
Traditional Probabilistic Risk Assessments (PRAs) model dependency through deterministic relationships in fault trees and event trees, or through empirical ratio common cause failure (CCF) models. However, popular CCF models do not recognized system specific defenses against dependencies and are restricted to identical components in redundant configuration.(More)
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