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- Publications
- Influence
IL-33 exacerbates antigen-induced arthritis by activating mast cells
- D. Xu, H. Jiang, +8 authors F. Liew
- Medicine
- Proceedings of the National Academy of Sciences
- 5 August 2008
IL-33, a cytokine of the IL-1 family, is closely associated with type II T cell responses. Here, we report an unexpected proinflammatory role of IL-33 in inflammatory arthritis. IL-33 was expressed… Expand
Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection
- J. Alves-Filho, F. Sônego, +8 authors F. Liew
- Biology, Medicine
- Nature Medicine
- 1 June 2010
Sepsis is a systemic inflammatory condition following bacterial infection with a high mortality rate and limited therapeutic options. Here we show that interleukin-33 (IL-33) reduces mortality in… Expand
The cytokine interleukin-33 mediates anaphylactic shock
- P. Pushparaj, H. Tay, +5 authors A. Melendez
- Medicine
- Proceedings of the National Academy of Sciences
- 16 June 2009
Anaphylactic shock is characterized by elevated immunoglobulin-E (IgE) antibodies that signal via the high affinity Fcε receptor (FcεRI) to release inflammatory mediators. Here we report that the… Expand
Interleukin-33 Induces Protective Effects in Adipose Tissue Inflammation During Obesity in Mice
- A. Miller, D. Asquith, +7 authors F. Liew
- Biology, Medicine
- Circulation research
- 3 September 2010
Rationale: Chronic low-grade inflammation involving adipose tissue likely contributes to the metabolic consequences of obesity. The cytokine interleukin (IL)-33 and its receptor ST2 are expressed in… Expand
IL-33 Exacerbates Autoantibody-Induced Arthritis
Rheumatoid arthritis pathogenesis comprises dysregulation in both innate and adaptive immunity. There is therefore intense interest in the factors that integrate these immunologic pathways in… Expand
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation
- J. Beale, Annabelle Jayaraman, +13 authors N. Bartlett
- Medicine
- Science Translational Medicine
- 1 October 2014
IL-25 critically links rhinovirus infection and allergic asthma exacerbations. IL-25 Horns in on Asthma Attacks The common cold isn’t so common in people with asthma. Rhinoviruses—the main causes of… Expand
The protective role of IL-13 in Experimental Autoimmune Myocarditis
- D. Čiháková, J. G. Barin, +10 authors N. Rose
- Medicine
- 1 April 2007
This information is current as Arthritis IL-33 Exacerbates Autoantibody-Induced
- H. Jiang, Yubin Li, +7 authors A. Melendez
- 2010
Anticorps dirigés contre il-25
- Andrew N. J. McKenzie, S. Ballantyne
- Medicine
- 17 April 2008
L'invention concerne l'anticorps 2C3 et des elements de liaison a la cible a base de 2C3 qui se situe a l'interleukine-25. Ceux-ci sont utiles en therapie, par exemple, dans le traitement de l'asthme.
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