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  • Wendy J. Potts, Jonathan Bowyer, +9 authors Rose A. Maciewicz
  • Biology, Medicine
  • International journal of experimental pathology
  • 2004 (First Published: 19 May 2004)
  • The role of cathepsin L in normal physiological processes was assessed using cathepsin L homozygous knockout mice (B6;129-Ctsl(tm1Alpk)). These mice were generated using gene targeting in embryonicContinue Reading
  • Mark M. Egerton, Michael I. Needham, +6 authors Matthew Hollis
  • Biology, Medicine
  • Journal of molecular endocrinology
  • 1995 (First Published: 1 April 1995)
  • The human breast carcinoma cell line T47D is known to express high-affinity calcitonin receptors (CTRs). PCR amplification of the CTR cDNA from T47D mRNA resulted in the identification of twoContinue Reading
  • M. Needham, Mark Egerton, +7 authors David Roger Johnstone
  • Biology, Medicine
  • Protein expression and purification
  • 1995 (First Published: 1 April 1995)
  • In order to demonstrate the potential of the LCR/MEL expression system for the expression of seven-transmembrane helix receptors the human calcitonin receptor (hCTR) has been cloned and expressed atContinue Reading
  • Scott Breen, Andrew Millest, B. E. Loveday, David Roger Johnstone, John C Waterton
  • Biology, Medicine
  • Calcified Tissue International
  • 1996 (First Published: 1 June 1996)
  • The use of peripheral quantitative computed tomography (pQCT) was investigated for the measurement of volumetric bone mineral density (BMD) in mg·cm−3. Two studies were undertaken. In the firstContinue Reading
  • St. Louis, David Roger Johnstone, Andrew Millest, Nicholas J. Russell, Graham J. Dockray
  • Medicine
  • Neuroscience
  • 1990 (First Published: 31 December 1990)
  • The influence of circulating antibodies to calcitonin gene-related peptide on the inflammatory response was examined in rats with adjuvant-induced arthritis. Rats were immunized with alpha calcitoninContinue Reading