Andrew McGill

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AIM To discover the causes of markedly raised ferritin levels in patients seen at a teaching hospital in Newcastle Upon Tyne, United Kingdom. METHODS Demographic and medical data were collected for all patients over 18 years who had a serum ferritin levels recorded as >=1500 microg/L during the period January to September 2002. The cause or causes for(More)
Pancreatic cancer (PC) evades immune destruction by favoring the development of regulatory T cells (Tregs) that inhibit effector T cells. The transcription factor Ikaros is critical for lymphocyte development, especially T cells. We have previously shown that downregulation of Ikaros occurs as a result of its protein degradation by the ubiquitin-proteasome(More)
(1) The sampler is electronically variable for both wash and sample time. The 60-position sample plate is removable. (2) Each pump and gear-box serves a pair of analytical platforms. Each pump has four speeds. There is one operating speed (5 rev./min.), one fast and two slow speeds. (3) The reagent valves have three positions, reagent, wash and a clamped(More)
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