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Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta-analysis.
PURPOSE To compare the clinical efficacy of leukotriene receptor antagonists with that of placebo, antihistamines, and nasal corticosteroids in patients with allergic rhinitis or nasal polyposis. … Expand
Dose response to inhaled corticosteroids : Benefits and risks
Searching MEDLINE, EMBASE, and BIDS were searched from 1966 to 1997. Search terms are listed. Papers with subject headings or an abstract in English were included. Abstracts from scientific sessions… Expand
Effects of adding either a leukotriene receptor antagonist or low-dose theophylline to a low or medium dose of inhaled corticosteroid in patients with persistent asthma.
STUDY OBJECTIVES To evaluate the effect of adding zafirlukast or low-dose theophylline to a beclomethasone dipropionate (BDP) extra-fine hydrofluoroalkane aerosol on bronchial hyperresponsiveness as… Expand
Dyslipidemia in Achilles tendinopathy is characteristic of insulin resistance.
- J. Gaida, Lotta Alfredson, Z. Kiss, Andrew M. Wilson, H. Alfredson, J. Cook
- Medicine and science in sports and exercise
UNLABELLED Overuse is considered to be a main causative factor for tendinopathies; however, recent reports indicate that tendinopathy is also common among both overweight and inactive individuals.… Expand
Peak inspiratory flow rate is more sensitive than acoustic rhinometry or rhinomanometry in detecting corticosteroid response with nasal histamine challenge.
Nasal histamine challenge testing is a standard method of assessing upper airway hyperreactivity although there is still debate as to the best measure of response. The aim of the study was to… Expand
Short-term repeatability and correlates of laboratory measures of nasal function in patients with seasonal allergic rhinitis.
The purpose of this study was to determine the variability of laboratory nasal function tests in 26 patients (18 female) with seasonal allergic rhinitis (SAR) (mean age 38.1 years). Their usual… Expand
Oral montelukast in acute asthma exacerbations: a randomised, double-blind, placebo-controlled trial
Background Although leukotriene receptor antagonists have an established role in the management of patients with chronic asthma, their efficacy in an acute asthma exacerbation is not fully known.… Expand
Importance of drug-device interaction in determining systemic effects of inhaled cor ticosteroids
5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists
- S. Fowler, I. Hall, Andrew M. Wilson, A. Wheatley, B. Lipworth
- Chemistry, Medicine
- European Journal of Clinical Pharmacology
- 17 May 2002
AbstractObjective. To determine whether genetic polymorphisms of the core promoter region of the 5-lipoxygenase gene contribute to the clinical response to leukotriene receptor antagonists. Methods.… Expand
Differences in lung bioavailability between different propellants for fluticasone propionate
The lung bioavailability (as adrenal suppression) of fluticasone propionate was about twofold greater with chlorofluorocarbons than hydrofluoroalkane as propellant. Direct switching between… Expand