Place cell firing patterns in the rat hippocampus are often organized as sequences. Sequences falling within cycles of the theta (6-10 Hz) local field potential (LFP) oscillation represent segments of ongoing behavioral trajectories. Sequences expressed during sharp wave ripple (SWR) complexes represent spatial trajectories through the environment, in both… (More)
Laboratory studies of decision making often take the form of two-alternative, forced-choice paradigms. In natural settings, however, many decision problems arise as stay/go choices. We designed a foraging task to test intertemporal decision making in rats via stay/go decisions. Subjects did not follow the rate-maximizing strategy of choosing only food items… (More)
Tolman proposed that complex animal behavior is mediated by the cognitive map, an integrative learning system that allows animals to reconfigure previous experience in order to compute predictions about the future. The discovery of place cells in the rodent hippocampus immediately suggested a plausible neural mechanism to fulfill the 'map' component of… (More)
The hippocampus and the orbitofrontal cortex (OFC) both have important roles in cognitive processes such as learning, memory and decision making. Nevertheless, research on the OFC and hippocampus has proceeded largely independently, and little consideration has been given to the importance of interactions between these structures. Here, evidence is reviewed… (More)
State representation is fundamental to behavior. However, identifying the true state of the world is challenging when explicit cues are ambiguous. Here, Bradfield and colleagues show that the medial OFC is critical for using associative information to discriminate ambiguous states.
Decision makers commit the sunk cost fallacy when they are influenced by previous investments instead of estimated future returns . As resources previously allocated toward an outcome are irrecoverable, adaptive choices should be based only on the future benefits that could result from available options. Humans clearly show sensitivity to sunk costs in a… (More)