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PURPOSE To document variation of transfusion practice following repair of hip fracture or cardiac surgery, as well as those requiring intensive care following a surgical intervention or multiple trauma (high risk patients). METHODS We documented rates of allogeneic red cell transfusion in 41,568 patients admitted to 11 hospitals across Canada between(More)
CONTEXT A number of countries have implemented a policy of universal leukoreduction of their blood supply, but the potential role of leukoreduction in decreasing postoperative mortality and infection is unclear. OBJECTIVE To evaluate clinical outcomes following adoption of a national universal prestorage leukoreduction program for blood transfusions. (More)
A life course epidemiology approach embraces the complexity of disease risk and acknowledges the long-term effects of physical, social, psychological, and behaviour pathways, operating across an individual's life, a community's generation, and a population's development, on health and well-being. Researchers who adopt a life course epidemiology approach(More)
Interest in the concept of knowledge translation (KT), one of the many terms used to describe the process(es) through which knowledge is transformed into action, is increasingly prevalent in the mainstream health literature. Despite a pressing need, little has been done to address the implications of evolving theories and strategies for KT in an Aboriginal(More)
The burden of cardiovascular disease and diabetes and associated risk factors, such as obesity, smoking, impaired glucose tolerance, hypertension, and dietary factors, present a mix of factors that are detrimental to the immediate and long-term health of First Nations peoples in Canada. The authors use a life course perspective to examine the long-term(More)
OBJECTIVE Creating effective and actionable research has become increasingly important for the health disciplines. Despite greater attention to knowledge translation (KT) in the health research, policy, and professional literature and the mounting need for strategic action to reduce the burden of ill health experienced by Aboriginal people in Canada, little(More)
PURPOSE Hereditary long QT syndrome is named for a prolonged QT interval reflecting predisposition to ventricular arrhythmias and sudden death. A high rate in a remote, northern Canadian First Nations community was brought to attention. METHODS Two severely affected index cases and 122 relatives were ascertained using community-based participatory(More)
BACKGROUND Stent thrombosis (ST) is rare, but is associated with significant morbidity and mortality. METHODS We analyzed data from the British Columbia (BC) Registry from April 2011-January 2012. RESULTS 101 ST cases were reported and verified. Based on timing, ST was considered early (≤30days) in 35.6%, late (>30days-1year) in 17.8% and very late(More)
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