Andrew M. Goldner

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Unidirectional influxes of sugars and Na from muscosal solution into the cells of rabbit ileum have been examined. The influxes of glucose, galactose, and 3-0-methyl glucose (3 MG) follow Michaelis-Menten type kinetics and are markedly dependent on the presence ofNa in the mucosal solution. For 3 MG, reduction of Na concentration causes a decrease in(More)
The effects of transport inhibitors on the movements of oxalate and chloride across the isolated short circuited rabbit colon were studied. Net oxalate absorption was shown in this species and was shown to be an energy dependent process as indicated by its sensitivity to 2-4 dinitrophenol (DNP) 10(-4)M. Mucosal addition of(More)
PEARSON, TERRY W., AND ANDREW M. GOLDNER. Calcium transport across avian uterus. II. Effects of inhibitors and nitrogen. Am. J. Physiol. 227(2) : 465-468. 1974.-Net calcium transport in the secretory direction occurs across the in vitro quail uterus in the absence of electrochemical gradients. The metabolic inhibitor, 2,4-dinitrophenol, and anaerobiosis(More)
Transepithelial calcium fluxes were measured across isolated uterus of laying, nonlaying, and molting quail under conditions where no electrochemical difference existed across the tissue. Net uterine transfer of calcium in molting and nonlaying birds occurs in the secretory direction and is approximately one-fifth the value obtained for laying birds. The(More)
Previous studies (Goldner, Schultz & Curran,J. Gen. Physiol. 1969,53:362) have suggested a direct coupling between influxes of sugars and Na across the brush border membrane of rabbit ileum. Effects of several inhibitors, ouabain, cyanide, dinitrophenol and iodoacetate on 3-O-methylglucose fluxes were examined in an effort to obtain information about(More)
PEARSON, TERRY W., AND ANDREW M. GOLDNER. Calcium transport across avian uterus. I. E$Ects of electro&e substitution. Am. J. Physiol. 225(6) : 1508-l 5 12. 1973.-Unidirectional calcium fluxes from serosa to mucosa (JS,, ) and mucosa to serosa (Jmds ) were determined across the isolated quail uterus. When the tissue was bathed with normal bicarbonate buffer,(More)
Since the proposal of the sodium-gradient hypothesis, research efforts have focused on two major areas: 1) establishing the thermodynamic efficacy of the electrochemical gradient for sodium as a driving force for uphill solute accumulation, and 2) determining the mechanism of energy coupling in cotransport systems. On the whole it is now reasonably well(More)