Learn More
The task of machine translation (MT) evaluation is closely related to the task of sentence-level semantic equivalence classification. This paper investigates the utility of applying standard MT evaluation methods (BLEU, NIST, WER and PER) to building clas-sifiers to predict semantic equivalence and entailment. We also introduce a novel classification method(More)
Activation of the human complement system of plasma proteins during immunological host defense can result in overproduction of potent proinflammatory peptides such as the anaphylatoxin C5a. Excessive levels of C5a are associated with numerous immunoinflammatory diseases, but there is as yet no clinically available antagonist to regulate the effects of C5a.(More)
1. Potent and highly selective small molecule antagonists have recently been developed by us for C5a receptors (C5aR) on human polymorphonuclear leukocytes (PMN). In this study we compared a new cyclic antagonist, F-[OPdChaWR], with an acyclic derivative, MeFKPdChaWr, for their capacities to bind to C5aR on human PMN and human umbilical artery membranes. We(More)
This paper describes a Bayesian framework for matching Delaunay triangulations. Relational structures of this sort are ubiquitous in intermediate level computer vision, being used to represent both Voronoi tessellations of the image plane and volumetric surface data. Our matching process is realised in terms of probabilistic relaxation. The novelty of our(More)
A new C5a receptor antagonist, the cyclic peptide Phe-[Orn-Pro-D-cyclohexylalanine-Trp-Arg], (F-[OPdChaWR]), was tested for its ability to antagonize the neutropenic effects of both C5a and endotoxin in rats. Human recombinant C5a (2 microg kg(-1) i.v.) caused rapid neutropenia, characterized by an 83% decrease in circulating polymorphonuclear leukocytes(More)
Activation of the human complement system of plasma proteins in response to infection or injury produces a 4-helix bundle glycoprotein (74 amino acids) known as C5a. C5a binds to G-protein-coupled receptors on cell surfaces triggering receptor-ligand internalization, signal transduction, and powerful inflammatory responses. Since excessive levels of C5a are(More)
This paper presents a technique for transliteration based directly on techniques developed for phrase-based statistical machine translation. The focus of our work is in providing a transliteration system that could be used to translate unknown words in a speech-to-speech machine translation system. Therefore the system must be able to generate arbitrary(More)