Learn More
  • Nick Howden, Ralph Rönnquist, Andrew Hodgson, Andrew Lucas
  • 2001
Intelligent Agents are being used for modelling simple rational behaviours in a wide range of distributed applications. In particular, multi-agent architectures based on the Belief-Desire-Intention model have been used successfully in situations where modelling of human reasoning and team behaviour are needed, such as simulating tactical decision-making in(More)
Air combat modelling using graphical simulation is a powerful means for development and evaluation of tactics. However, large models are particularly expensive and time-consuming to maintain and modify. Multi-aircraft full mission man-in-the-loop simulators will provide an even more complex programming environment. Agent-oriented architecture provides a(More)
This paper describes research into automated support for air traac controllers performing tactical air traac management. It describes the OASIS system developed to help alleviate air traac congestion. The system achieves this by maximizing runway utilization, achieved through arranging landing aircraft into an optimal order, assigning them a landing time,(More)
Many modern manufacturing systems are highly automated and are now requiring decentralised 'smart' architectures to control hardware and manage the flow of materials / knowledge, in order to provide responsiveness. This responsiveness is needed to satisfy an ever increasing consumer need for goods that satisfy their unique requirements and are delivered to(More)
We provide Ising formulations for many NP-complete and NP-hard problems, including all of Karp's 21 NP-complete problems. This collects and extends mappings to the Ising model from partitioning, covering and satisfiability. In each case, the required number of spins is at most cubic in the size of the problem. This work may be useful in designing adiabatic(More)
Idiosyncratic adverse drug reactions are unpredictable, dose-independent and potentially life threatening; this makes them a major factor contributing to the cost and uncertainty of drug development. Clinical data suggest that many such reactions involve immune mechanisms, and genetic association studies have identified strong linkages between drug(More)
We reported previously that a proportion of natural CD25(+) cells isolated from the PBMC of HCV patients can further upregulate CD25 expression in response to HCV peptide stimulation in vitro, and proposed that virus-specific regulatory T cells (Treg) were primed and expanded during the disease. Here we describe epigenetic analysis of the FOXP3 locus in(More)
Air traac worldwide continued to grow in 1993, despite the medium-term eeects of the recession in many countries. The direct and indirect costs attributable to air traac congestion are already enormous, and are predicted to rise to US$10 billion in Europe alone. The challenge is to match the demand with the available capacity. The alternatives are to(More)