Andrew Leung

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Recent multiple sclerosis (MS) MRI research has highlighted the need to move beyond the lesion-centric view and to develop and validate new MR imaging strategies that quantify the invisible burden of disease in the brain and establish much more sensitive and specific surrogate markers of clinical disability. One of the most promising of such measures is(More)
INTRODUCTION As a vital part of the inflammatory response, the leukocyte adhesion cascade involves the capture of white blood cells at the vascular endothelium, a progressively slowing, " rolling " motion of cells along the vessel walls, firm cell adhesion at target sites, and eventually, the transmigration of activated cells into the inflamed tissue 1-4(More)
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