Andrew Koll

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We report on a micromachined calorimetric chemical sensor for volatile organic compounds in air fabricated in industrial CMOS technology. The sensor measures enthalpy changes during absorption and desorption of a gaseous analyte into a chemically selective polymer. The enthalpy changes cause temperature variations of a thermally insulated micromachined(More)
In the present study, some new amides of 5-amino-3-methylisoxazole-4-carboxylic acid were obtained. All new structures possessed markedly different groups of electron acceptor character, different spatial structure and they contained nitrogen heteroatom, enabling formation of salts and, at the same time, higher biological availability. They were examined(More)
ELISA testing using anti-HCP (host cell protein) antibodies remains the work-horse for detecting host cell protein in recombinant drug substances. [1] ELISA antibodies (ab) are generated against numerous host cell proteins by different B cell lineages within an animal. Each antibody must be tested to ensure broad reactivity with many proteins. A narrow(More)
Inhibitory doses (ID50) of phenols complexed with dicyclohexylamine are lower (21.4-47.7%) than the inhibitory doses of free phenols. This is demonstrated in vitro by experiments with Aspergillus oryzae and Penicillium expansum on solid medium.
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