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BACKGROUND Depression is a major individual and public-health burden throughout the world and is managed mainly in primary care. The most effective strategy to reduce this burden has been believed to be education of primary-care practitioners. We tested this assumption by assessing the effectiveness of an educational programme based on a clinical-practice(More)
BACKGROUND To determine the effectiveness of home-based cardiac rehabilitation programmes compared with (i) usual care and (ii) supervised centre-based cardiac rehabilitation on mortality, health related quality of life and modifiable cardiac risk factors of patients with coronary heart disease. METHODS Systematic review and meta-analysis of randomised(More)
BACKGROUND Health inequalities exist for many disorders, but the contribution of deprivation to the prevalence and outcome of depressive symptoms in primary care populations has been infrequently studied. AIMS To examine the influence of Jarman under-privileged area (UPA) scores on the prevalence and outcome of depressive symptoms in general practice(More)
OBJECTIVES To research the lay public's understanding of equipoise and randomisation in randomised controlled trials (RCTs) and to look at why information on this may not be not taken in or remembered, as well as the effects of providing information designed to overcome barriers. DESIGN Investigations were informed by an update of systematic review on(More)
The requirements of the UK Equality Act 2010 and some high profile criticism for using a potentially ageist methodology have prompted the National Institute for Health and Clinical Excellence (NICE) to assess the processes and methodology it uses to make appraisal decisions. This paper argues that NICE has established rigorous systems to protect against(More)
OBJECTIVE To compare the outcomes of home-based (using the Heart Manual) and centre-based cardiac rehabilitation programmes. DESIGN Randomised controlled trial and parallel economic evaluation. SETTING Predominantly inner-city, multi-ethnic population in the West Midlands, England. PATIENTS 525 patients referred to four hospitals for cardiac(More)
OBJECTIVE To describe the current methods used by English medical schools to identify prospective medical students for admission to the five year degree course. DESIGN Review study including documentary analysis and interviews with admissions tutors. SETTING All schools (n = 22) participating in the national expansion of medical schools programme in(More)