Andrew J. Hinkle

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The effects of 10% methohexital (pH 10 and osmolarity 820) on the mucosal lining of the mouse rectum was examined after transrectal instillation and application to a rectal mucosal pouch. In addition to 10% methohexital, control solutions of pH 4, 7, 12, and osmolarities of 823 mOsm/1, 1027 mOsm/1, and 1372 mOsm/1 were also applied to the rectal pouch.(More)