Andrew J. Hall

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OBJECTIVE To examine whether the observed excess of childhood leukaemia and lymphoma near the Sellafield nuclear plant is associated with established risk factors or with factors related to the plant. DESIGN A case-control study. SETTING West Cumbria health district. SUBJECTS 52 Cases of leukaemia, 22 of non-Hodgkin's lymphoma, and 23 of Hodgkin's(More)
BACKGROUND Melioidosis, or infection with Pseudomonas pseudomallei is an important cause of morbidity and mortality in South East Asia and Northern Australia. The epidemiology of melioidosis in Ubon Ratchatani, Northeast Thailand was studied over a 5-year period from 1987 to 1991. METHODS Rates and, when possible, the risks of developing melioidosis were(More)
Dundonald), A K Sharma (University Hospital Aintree, Liverpool), K R Lees (Western Infirmary, Glasgow), and D G Smithard (William Harvey Hospital, Ashford, Kent). Contributors: See bmj.com Funding: This project was supported by an unrestricted grant from Boehringer Ingelheim. Competing interests: LK and MMB have been reimbursed by Boehringer Ingelheim to(More)
Aflatoxins are dietary contaminants that are hepatocarcinogenic and immunotoxic and cause growth retardation in animals, but there is little evidence concerning the latter two parameters in exposed human populations. Aflatoxin exposure of West African children is known to be high, so we conducted a longitudinal study over an 8-month period in Benin to(More)
BACKGROUND Growth faltering in West African children has previously been associated with dietary exposure to aflatoxins, particularly upon weaning. However, in animal studies in utero exposure to low levels of aflatoxin also results in growth faltering. OBJECTIVE This study investigated the effect of in utero aflatoxin exposure on infant growth in the(More)
BACKGROUND Dietary exposure to high levels of the fungal toxin, aflatoxin, occurs in West Africa, where long-term crop storage facilitates fungal growth. METHODS We conducted a cross-sectional study in Benin and Togo to investigate aflatoxin exposure in children around the time of weaning and correlated these data with food consumption, socioeconomic(More)
BACKGROUND Aflatoxins are fungal metabolites that frequently contaminate staple foods in much of sub-Saharan Africa, and are associated with increased risk of liver cancer and impaired growth in young children. We aimed to assess whether postharvest measures to restrict aflatoxin contamination of groundnut crops could reduce exposure in west African(More)
AIMS To assess the effect of statins on a range of health outcomes. METHODS We undertook a population-based cohort study to assess the effect of statins on a range of health outcomes using a propensity score-based method to control for differences between people prescribed and not prescribed statins. We validated our design by comparing our results for(More)
BACKGROUND There is evidence that chronic inflammation may promote atherosclerotic disease. We tested the hypothesis that acute infection and vaccination increase the short-term risk of vascular events. METHODS We undertook within-person comparisons, using the case-series method, to study the risks of myocardial infarction and stroke after common(More)
Reactivation of latent varicella zoster virus as herpes zoster is thought to result from waning of specific cell-mediated immunity, but little is known about its determinants in individuals with no underlying immunosuppression. We systematically reviewed studies of zoster epidemiology in adults and analysed data from a large morbidity study to identify(More)