Andrew Higgins

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This paper describes the development and use of a model designed to optimise train schedules on single line rail corridors. The model has been developed with two major applications in mind, namely: as a decision support tool for train dispatchers to schedule trains in real time in an optimal way; and as a planning tool to evaluate the impact of timetable(More)
Scheduling of trains on a single line involves using train priorities for the resolution of conflicts. The mathematical programming model described in the first part of this paper schedules trains over a single line track when the priority of each train in a conflict depends on an estimate of the remaining crossing and overtaking delay. This priority is(More)
Oral administration of altrenogest for oestrus suppression in competition horses is believed to be widespread in some equestrian disciplines, and can be administered continuously for several months during a competition season. To examine whether altrenogest has any anabolic or other potential performance enhancing properties that may give a horse an unfair(More)
A recent article in Genetics looked at population structure, genetic diversity and inbreeding in purebred dogs, not least as dogs are being used increasingly as models of human diseases (Calboli et al., 2008). The authors accessed the UK Kennel Club’s extensive registration database and analysed the pedigrees of 10 breeds with relatively large numbers of(More)
Problem-based learning (PBL) has now been introduced in at least one of its various taxonomic forms in most dental curricula. We recently developed a novel form of PBL, referred to as Context Rich Problems, which we implemented in the Oral Biology course at the Otago University Dental School. A unique event, the teaching of second and third year students in(More)
Several orphan G protein-coupled receptors, including GPR40, have recently been shown to be responsive to fatty acids. Although previous reports have suggested GPR40 detects medium- and long-chain fatty acids, it has been reported to be unresponsive to short chain fatty acids. In this study, we have heterologously expressed mouse GPR40 in Xenopus laevis(More)
The Australian sugar industry is seeking to increase profitability through better integration across a value chain fragmented among many owners. Within the cane harvesting and transport sectors, many existing inefficiencies are a result of excessive numbers of harvesting machines owned by harvester contractors and growers, and the fact that most harvesters(More)