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In this paper, we give a status report of a real-world application scenario that uses two distinct types of workflow within the Triana problem solving environment: serial scientific workflow for the data processing of gravitational waves signals; and the distributed workflows that dynamically map to the virtual Grid overlay of Triana services. We briefly(More)
In this paper, we describe the graphical abstractions for Grids and services that have been implemented within the Triana problem solving environment. We provide an overview of the ways in which Triana interacts with services (e.g., Web and P2P services) and then how we interact with core Grid components, such as resource managers and data management(More)
BACKGROUND Affymetrix GeneChip technology enables the parallel observations of tens of thousands of genes. It is important that the probe set annotations are reliable so that biological inferences can be made about genes which undergo differential expression. Probe sets representing the same gene might be expected to show similar fold changes/z-scores,(More)
BACKGROUND High Density Oligonucleotide arrays (HDONAs), such as the Affymetrix HG-U133A GeneChip, use sets of probes chosen to match specified genes, with the expectation that if a particular gene is highly expressed then all the probes in that gene's probe set will provide a consistent message signifying the gene's presence. However, probes that contain a(More)
We describe various types of outliers seen in Affymetrix GeneChip data. We have been able to utilise the data in the Gene Expression Omnibus to screen GeneChips across a range of scales, from single probes, to spatially adjacent fractions of arrays, to whole arrays, to whole experiments. In this review we describe a number of causes for why some reported(More)
There is a pressing need for the archiving and curation of raw X-ray diffraction data. This information is critical for validation, methods development and improvement of archived structures. However, the relatively large size of these data sets has presented challenges for storage in a single worldwide repository such as the Protein Data Bank archive. This(More)