Andrew Fry

Julian Forton2
Anna Richardson2
2Julian Forton
2Anna Richardson
2Kirk Rockett
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BACKGROUND Localising regulatory variants that control gene expression is a challenge for genome research. Several studies have recently identified non-coding polymorphisms associated with inter-individual differences in gene expression. These approaches rely on the identification of signals of association against a background of variation due to other(More)
During mitosis, human cells exhibit a peak of protein phosphorylation that alters the behaviour of a significant proportion of proteins, driving a dramatic transformation in the cell's shape, intracellular structures and biochemistry. These mitotic phosphorylation events are catalysed by several families of protein kinases, including Auroras, Cdks, Plks,(More)
BACKGROUND During malaria infection the Toll-like receptor 9 (TLR9) is activated through induction with plasmodium DNA or another malaria motif not yet identified. Although TLR9 activation by malaria parasites is well reported, the implication to the susceptibility to severe malaria is not clear. The aim of this study was to assess the contribution of(More)
SOAP, a de-facto communication protocol of Web services, is popular for its interoperability across organisations. However, SOAP is based on XML and therefore inherits XML's disadvantage of having voluminous messages. When there are many transactions requesting similar server operations, using conventional SOAP unicast to send SOAP response messages can(More)
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