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  • Andrew E. Firth, Ian Brierley
  • Biology, Medicine
  • The Journal of general virology
  • 2012 (First Publication: 1 July 2012)
  • Viral protein synthesis is completely dependent upon the translational machinery of the host cell. However, many RNA virus transcripts have marked structural differences from cellular mRNAs thatExpand
  • Ezequiel Balmori Melian, Edward E Hinzman, +9 authors Alexander A Khromykh
  • Biology, Medicine
  • Journal of Virology
  • 2009 (First Publication: 11 November 2009)
  • ABSTRACT Flavivirus NS1 is a nonstructural protein involved in virus replication and regulation of the innate immune response. Interestingly, a larger NS1-related protein, NS1′, is often detectedExpand
  • Ying Fang, Emmely E. Treffers, +8 authors Andrew E. Firth
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2012 (First Publication: 4 October 2012)
  • Programmed −1 ribosomal frameshifting (−1 PRF) is a gene-expression mechanism used to express many viral and some cellular genes. In contrast, efficient natural utilization of −2 PRF has not beenExpand
  • Andrew E. Firth, John F. Atkins
  • Medicine, Biology
  • Virology Journal
  • 2008 (First Publication: 5 February 2009)
  • Japanese encephalitis, West Nile, Usutu and Murray Valley encephalitis viruses form a tight subgroup within the larger Flavivirus genus. These viruses utilize a single-polyprotein expressionExpand