Andrew Dwyer

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Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is the acquisition of serial MRI images before, during, and after the administration of an MR contrast agent. Unlike conventional enhanced MRI, which simply provides a snapshot of enhancement at one point in time, DCE-MRI permits a fuller depiction of the wash-in and wash-out contrast kinetics(More)
PURPOSE To describe the abdominal computed tomographic (CT) and ultrasonographic (US) findings in patients with thoracic lymphangioleiomyomatosis (LAM) and to relate the prevalence of the findings to the severity of pulmonary disease. MATERIALS AND METHODS Eighty patients with LAM underwent chest and abdominopelvic CT and abdominopelvic US. The images(More)
The significance of linear regions of altered signal intensity that appear in sagittal magnetic resonance (MR) images along the length of the spinal cord was investigated. Examinations were performed on ten healthy volunteers and one patient with spinal cord edema. A 0.5-T or a 1.5-T MR system was used. Sampling-related effects (Gibbs phenomenon) at spinal(More)
PURPOSE To retrospectively compare the frequencies of computed tomographic (CT) findings in patients with lymphangioleiomyomatosis (LAM) and patients with tuberous sclerosis complex (TSC) and LAM. MATERIALS AND METHODS Institutional review board approval and informed consent were obtained for the HIPAA-compliant study. In 256 patients with LAM (mean age,(More)
The histologic type of adrenal tumors can be accurately predicted by MRI on the basis of their signal intensity on a T2-weighted image. However, a small but significant number of nonfunctioning adenomas, carcinomas, and metastases cannot be differentiated because they have similar signal intensities on a spin-echo 2500/80 scan. Eight (21%) of 38 of these(More)
Neonatal onset multisystem inflammatory disease (NOMID), an autoinflammatory disease, is characterized by fever, chronic urticarial rash, CNS manifestations, and arthropathy. Approximately 50% of patients with NOMID have de novo missense mutations in CIAS1, which is associated with modulation of the IL-1b and apoptotic pathways. Approximately 60% of NOMID(More)
PURPOSE To evaluate the imaging and clinical features of lymphangioleiomyomas and to describe the phenomenon of diurnal variation in the size of lymphangioleiomyomas in patients with lymphangioleiomyomatosis. MATERIALS AND METHODS One hundred twenty-eight patients with lymphangioleiomyomatosis underwent chest and abdominopelvic computed tomography (CT).(More)
Inversion recovery (IR), commonly considered a pulse sequence capable of producing T1-weighted images with excellent display of normal anatomy, is versatile: The null point and peak time provide a useful, succinct summary of the properties of IR and its capacity for producing both T1- and T2-weighted images. Shortening of the inversion time (TI) and(More)
OBJECTIVE The purpose of the study is to describe the appearance of the posterior tibialis tendon on MR imaging and high-resolution sonography with color and power Doppler imaging and to determine whether sonography is as accurate for diagnosing tendinosis as MR imaging. SUBJECTS AND METHODS Fifteen healthy volunteers and 31 patients (44 tendons) who were(More)