Skip to search formSkip to main contentSkip to account menu
Feasibility of Pathways for Transfer of Acyl Groups from Mitochondria to the Cytosol to Form Short Chain Acyl-CoAs in the Pancreatic Beta Cell*
TLDR
The results indicate beta cells possess enzyme pathways that can incorporate carbon from glucose into acetyl-CoA, acetoacetyl- CoA, and succinyl- coA and carbon from leucine into these three SC-CoAs plus HMG-Coa in their mitochondria and enzymes that can form acetyl, coA,acetoacetate, malonyl-Co a, and HMG -CoA in their cytosol.
View on Publisher
N-Heterocyclic carbene catalysed beta-lactam synthesis.
N-Heterocyclic carbenes promote the formal [2+2] cycloaddition of ketenes with N-tosyl imines to give the corresponding beta-lactams in good to excellent isolated yields; chiral NHCs give…
View on PubMed
The conjugate addition of enantiomerically pure lithium amides as homochiral ammonia equivalents: scope, limitations and synthetic applications
View via Publisher
Selective and catalytic carbon dioxide and heteroallene activation mediated by cerium N-heterocyclic carbene complexes† †Electronic supplementary information (ESI) available. CCDC 1856101–1856106,…
A series of rare earth complexes of the form Ln(LR)3 supported by bidentate ortho-aryloxide–NHC ligands are reported (LR = O(o-C6H2–tBu2-2,6-CN(C2H2)NR); R = iPr, tBu, Mes; Ln = Ce, Sm, Eu).
View PDF
Asymmetric synthesis of N,O,O,O-tetra-acetyl d-lyxo-phytosphingosine, jaspine B (pachastrissamine), 2-epi-jaspine B, and deoxoprosophylline via lithium amide conjugate addition.
TLDR
The highly diastereoselective anti-aminohydroxylation of (E)-gamma-tri-iso-propylsilyloxy-alpha,beta-unsaturated esters, via conjugate addition of lithium, has been used as the key step in the asymmetric synthesis of N,O, O,O-tetra-acetyl d-lyxo-phytosphingosine.
View on PubMed
Enantioselective Synthesis of β-Fluoro-β-aryl-α-aminopentenamides by Organocatalytic [2,3]-Sigmatropic Rearrangement.
TLDR
The tetramisole-promoted catalytic enantioselective [2,3]-sigmatropic rearrangement of quaternary ammonium salts bearing a (Z)-3-fluoro-3-arylprop-2-ene group generates a range of β- fluoro-β-aryl-α-aminopentenamides containing a stereogenic tertiary fluorine substituent.
View on PubMed
Asymmetric synthesis of (4R,5R)-cytoxazone and (4R,5S)-epi-cytoxazone.
TLDR
The synthesis of the C(5)-epimer, (4R,5S)-epi-cytoxazone in 44% overall yield, has been completed via a protocol involving N-Boc protection of the primary [small beta]-amino ester and subsequent reduction.
View on PubMed
Sulfur–sulfur bonding in the amorphous sulfides WS3, WS5, and Re2S7 from sulfur K-edge EXAFS studies
The measurement of extended X-ray absorption fine structure (EXAFS) using energy-selective fluorescence detection in the soft X-ray region has enabled sulfur K-edge EXAFS studies of the amorphous…
View via Publisher
Asymmetric total synthesis of sperabillins B and D via lithium amide conjugate addition.
TLDR
Diastereoselective conjugate addition of homochiral lithium (R)-N-allyl-N-alpha-methylbenzylamide to methyl (2E,5E)-hepatadienoate allows a concise route to the core fragment, methyl (3R,5R,6R)-3,6-diamino-5-hydroxyheptanoate, of sperabillins B and D.
View on PubMed
Chiral relay in NHC-mediated asymmetric β-lactam synthesis II; asymmetry from NHCs derived from acyclic 1,2-diamines
View via Publisher
...
...
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License