Andrew D . Sauter

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A new contact-free, small droplet deposition method using an induction-based fluidics (IBF) technique to dispense nanoliter drops is described and evaluated for sample preparation in matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS). The signal intensities available when using nanoliter spots are greater than those obtained with(More)
This study preliminarily investigates whether nanoliter volumes of concentrated polar liquids and organic monomers launched to targets using induction based fluidics (IBF) can be verified through the real time charge measurements. We show that using a nanoliter IBF dispensing device and nanocoulomb meter, charge measurements made on nanoliter drops in real(More)
Induction based fluidics (IBF), a new, simple patented approach for transporting liquids in the micro and the macro world, is discussed. Electric fields are shown to energize liquid/s in a container/s to execute an array of purposes. IBF is shown uniquely to energize N liquids in simple off the shelf devices, inductively. We discuss calibration and other(More)
Electrospray ionization mass spectra of lanthanide coordination complexes were measured by launching nanoliter-sized droplets directly into the aperture of an electrospray ionization mass spectrometer. Droplets ranged in size from 102 nL to 17 nL, while metal concentrations were 293 μM. The sample solution was delivered to a source capillary by a nanoliter(More)
Here, we report the utility of induction-based fluidics (IBF) for the introduction of oligonucleotides to a mass spectrometer via charged droplets. The device produces nanoliter-sized droplets, which are field transported with minimal concerns related to source plugging or sampling loss. The IBF source enabled detection of oligonucleotides at the nanomolar(More)
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