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This article investigates the problem of how language learners decipher what words mean. In many recent models of language evolution, agents are provided with innate meanings a priori and explicitly transfer them to each other as part of the communication process. By contrast, I investigate how successful communication systems can emerge without innate or(More)
Cross-situational learning is a mechanism for learning the meaning of words across multiple exposures, despite exposure-by-exposure uncertainty as to the word's true meaning. We present experimental evidence showing that humans learn words effectively using cross-situational learning, even at high levels of referential uncertainty. Both overall success(More)
Next-generation DNA sequencing technologies have revolutionized diverse genomics applications, including de novo genome sequencing, SNP detection, chromatin immunoprecipitation, and transcriptome analysis. Here we apply deep sequencing to genome-scale fitness profiling to evaluate yeast strain collections in parallel. This method, Barcode analysis by(More)
The cause of Crohn's disease (CD) remains poorly understood. Counterintuitively, these patients possess an impaired acute inflammatory response, which could result in delayed clearance of bacteria penetrating the lining of the bowel and predispose to granuloma formation and chronicity. We tested this hypothesis in human subjects by monitoring responses to(More)
We present a mathematical model of cross-situational learning , in which we quantify the learnability of words and vocabularies. We find that high levels of uncertainty are not an impediment to learning single words or whole vocabulary systems, as long as the level of uncertainty is somewhat lower than the total number of meanings in the system. We further(More)
This paper investigates the development of experience-based meaning creation and explores the problem of establishing successful communication systems in a population of agents. The aim of the work is to investigate how such systems can develop, without reliance on phenomena not found in actual human language learning, such as the explicit transmission of(More)
Cross-situational learning is a mechanism for learning the meaning of words across multiple exposures, despite exposure-by-exposure uncertainty as to a word's true meaning. Doubts have been expressed regarding the plausibility of cross-situational learning as a mechanism for learning human-scale lexicons in reasonable timescales under the levels of(More)
Next-generation sequencing has proven an extremely effective technology for molecular counting applications where the number of sequence reads provides a digital readout for RNA-seq, ChIP-seq, Tn-seq and other applications. The extremely large number of sequence reads that can be obtained per run permits the analysis of increasingly complex samples. For(More)