Andrew D. Firth

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one-dimensional task similar to that used by Accot and Zhai (2002). The experimental interface consisted of a six-pixel diameter dot placed some distance from the six-pixel wide grey target line in the middle of the window (Figure 1a). Participants clicked on the dot to start each task and then acquired the line as quickly as possible. Software logged the(More)
High-throughput somatic mutation screening using FFPE tissues is a major challenge because of a lack of established methods and validated variant calling algorithms. We aimed to develop a targeted sequencing protocol by Fluidigm multiplex PCR and Illumina sequencing and to establish a companion variant calling algorithm. The experimental protocol and(More)
BACKGROUND The demand for total hip arthroplasty (THA), total knee arthroplasty (TKA), and unicompartmental knee arthroplasty (UKA) is growing rapidly because of the proven success of these procedures and an increase in the aging population. However, resources are limited and health-care budgets are finite. Recently, a number of care providers have started(More)
The Star Excursion Balance Test (SEBT) is an eight-direction, maximal-reach balance test whose measurement properties are unknown in participants with chronic patellar instability. We designed an observational study with repeated measures to evaluate the test-retest reliability, cross-sectional and longitudinal construct validity, sensitivity to change and(More)
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