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We propose a space-time stick-breaking process for the disease cluster estimation. The dependencies for spatial and temporal effects are introduced by using space-time covariate dependent kernel stick-breaking processes. We compared this model with the space-time standard random effect model by checking each model’s ability in terms of cluster detection of(More)
Despite interest in the built food environment, little is known about the validity of commonly used secondary data. The authors conducted a comprehensive field census identifying the locations of all food outlets using a handheld global positioning system in 8 counties in South Carolina (2008-2009). Secondary data were obtained from 2 commercial companies,(More)
In this article, we consider methods for Bayesian computation within the context of brain imaging studies. In such studies, the complexity of the resulting data often necessitates the use of sophisticated statistical models; however, the large size of these data can pose significant challenges for model fitting. We focus specifically on the(More)
A range of point process models which are commonly used in spatial epidemiology applications for the increased incidence of disease are compared. The models considered vary from approximate methods to an exact method. The approximate methods include the Poisson process model and methods that are based on discretization of the study window. The exact method(More)
There has long been a recognition that place matters in health, from recognition of clusters of yellow fever and cholera in the 1800s to modern day analyses of regional and neighborhood effects on cancer patterns. Here we provide a summary of discussions about current practices in the spatial analysis of georeferenced cancer data by a panel of experts(More)
BACKGROUND There is increasing interest in the study of place effects on health, facilitated in part by geographic information systems. Incomplete or missing address information reduces geocoding success. Several geographic imputation methods have been suggested to overcome this limitation. Accuracy evaluation of these methods can be focused at the level of(More)
BACKGROUND: Interest in the development of statistical methods for disease cluster detection has experienced rapid growth in recent years. Evaluations of statistical power provide important information for the selection of an appropriate statistical method in environmentally-related disease cluster investigations. Published power evaluations have not yet(More)
BACKGROUND European ecologic studies suggest higher socioeconomic status is associated with higher incidence of type 1 diabetes. Using data from a case-control study of diabetes among racially/ethnically diverse youth in the United States (U.S.), we aimed to evaluate the independent impact of neighborhood characteristics on type 1 diabetes risk. Data were(More)
In spatial epidemiology, a scaling effect due to an aggregation of data from a finer to a coarser level is a common phenomenon. This article focuses on addressing this issue using a hierarchical Bayesian modeling framework. We propose three different multiscale models. The first two models use a shared random effect that the finer level inherits from the(More)
We conducted an ecological analysis of childhood acute lymphoblastic leukaemia-incidence data from children <or=5 years old during 1992-1998 from the Surveillance, Epidemiology, and End Results Program in 200 counties and Hawaii. The response variable was the count of cases in each county race-sex stratum, examined in relation to data from the United States(More)