Dysfunction of the dorsolateral prefrontal cortex (DLPFC) in schizophrenia is associated with lamina-specific alterations in particular subpopulations of interneurons. In pyramidal cells, postsynaptic γ-aminobutyric acid (GABA(A)) receptors containing different α subunits are inserted preferentially in distinct subcellular locations targeted by inputs from… (More)
THEGREATARGENTINIAN (1964)wrote a story called WRITER JORGE LLXBORGES " The Library of Babel " describing a magnificent, endless library: [I]ts shelves register all the possible combinations of the twenty-odd orthographical symbols.. .. In other words, all that it is given to express, in all languages. Everything: the minutely detailed history of the… (More)
BACKGROUND Diabetes is associated with a cardiomyopathy that is independent of coronary artery disease or hypertension. In the present study we used in vivo magnetic resonance imaging (MRI) and echocardiographic techniques to examine and characterize early changes in myocardial function in a mouse model of type 1 diabetes. METHODS Diabetes was induced in… (More)
BACKGROUND The lymphatics form a second circulatory system that drains the extracellular fluid and proteins from the tumor microenvironment, and provides an exclusive environment in which immune cells interact and respond to foreign antigen. Both cancer and inflammation are known to induce lymphangiogenesis. However, little is known about bladder lymphatic… (More)
and four anonymous reviewers for their generous assistance, comments and suggestions.
PURPOSE To apply diffusion tensor images using 30 noncollinear directions for diffusion-weighted gradient schemes to characterize diffusion tensor imaging (DTI) features associated with C6 glioma-bearing rat brains, and ideally visualize fiber tractography datasets. MATERIALS AND METHODS Fiber tractographies of normal male Fischer 344 rat brains were… (More)