Andrew A. Duncan

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BACKGROUND Frontal plane trunk and lower extremity adjustments during unanticipated tasks are hypothesized to influence hip and knee neuromuscular control, and therefore, contribute to anterior cruciate ligament (ACL) injury risk. The aims of this study were to examine frontal plane trunk/hip kinematics and hip and knee moments (measures of neuromuscular(More)
STUDY DESIGN Two-factor mixed-design study, with factors including group (control and noncoper) and task (sidestep, crossover, and straight). OBJECTIVES To compare the knee and hip joint angles and moments of control subjects and subjects with an anterior cruciate ligament (ACL) deficient knee classified as noncopers, during a sidestep, crossover, and(More)
This paper reports on the design issues and subsequent performance of a soft intellectual property (IP) core implementation of a self-organizing neural network. The design is a development of a previous 0.65-/spl mu/m single silicon chip providing an array of 256 neurons, where each neuron stores a 16 element reference vector. Migrating the design to a soft(More)
The percentage dose of lactulose and mannitol excreted in urine after oral ingestion is used as a noninvasive method of assessing small intestinal permeability. The collection of incomplete or inaccurately timed urine samples can lead to errors in estimation of sugar probe molecules. We describe an HPLC method for the simultaneous determination of lactulose(More)
The collagen crosslinks, pyridinoline and deoxypyridinoline, have been developed as urinary markers of bone resorption but, despite wide clinical application of the technique, comparatively little attention has been paid to the standardization of these compounds. In this study, pyridinoline and deoxypyridinoline have been purified from bone and converted(More)
High-performance liquid chromatography methods were developed to measure the concentration of hydroxypyridinium crosslinks in the intramuscular collagen and tendinous parts of functionally different skeletal muscles at different ages. A significant increase in pyridinoline concentration took place during maturation reaching 0.32 +/- 0.07 (mol/mol collagen)(More)