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BACKGROUND Previous studies have shown increases in experimental pain during induction of a negative emotion with visual stimuli, verbal statements or unpleasant odours. The goal of the present study was to analyse the spatio-temporal activation patterns underlying pain augmentation during negative emotional sounds. METHODS Negative (e.g., crying),(More)
Noxious stimulation activates-in addition to the brain structures related to sensory, emotional, and cognitive components of pain-also the brain's motor system. Effect of noxious input on the primary motor (MI) cortex remains, however, poorly understood. To characterize this effect in more detail, we quantified the ongoing oscillatory communication between(More)
PURPOSE To compare manual volumetry of gray matter (GM) / white matter (WM) of Broca's area subparts: pars opercularis (POP) and pars triangularis (PTR) in both hemispheres between musicians and nonmusician, as it has been shown that these regions are crucial for musical abilities. A previous voxel-based morphometric (VBM) study conducted in our laboratory(More)
If corpus callosum (CC) mediates the activation of the secondary somatosensory area (SII) ipsilateral to the side of stimulation, then the peak latencies of the contra- and ipsilateral SII activity as well as the amplitude of the ipsilateral SII activity should correlate with the size of CC. Innocuous electrical stimuli of five different intensities were(More)
Fibromyalgia syndrome is a chronic pain disorder characterised by widespread pain and tenderness in muscles and deep tissues. Current theories regarding the pathophysiological origins of fibromyalgia syndrome point towards central sensitisation and a decreased capacity of descending nociceptive controls. Morphological alterations to subcortical brain(More)
Reduced amplitude of the cortical P300 event-related potential (ERP) component during response inhibition is associated with vulnerability to alcohol use disorders. In the current study, we investigated the effect of an experimental manipulation of response conflict on the amplitude of the P300 component during response inhibition, and examined whether(More)
Negative emotions have been shown to augment experimental pain. As induced emotions alter brain activity, it is not clear whether pain augmentation during noxious stimulation would be related to neural activation existing prior to onset of a noxious stimulus or alternatively, whether emotional stimuli would only alter neural activity during the period of(More)
This work was conducted to study the plasticity of superior (SCP) and middle (MCP) cerebellar peduncles in musicians. The cerebellum is well known to support several musically relevant motor, sensory and cognitive functions. Previous studies reported increased cerebellar volume and grey matter (GM) density in musicians. Here, we report on plasticity of(More)
Repetition suppression (RS) relates to a reduced neuronal response to a stimulus that is repeated. This phenomenon has been observed in the visual ventral stream and other sensory modalities, suggesting that it is a common feature of neuronal processing. Whilst a number of different models have been suggested to explain the underlying neural mechanisms of(More)
OBJECTIVE To evaluate cortical activation patterns during mechanical-tactile stimulation in fibromyalgia syndrome (FMS) patients and to correlate cortical activation changes with clinical symptoms. METHODS Nineteen female FMS patients and 18 matched, healthy control subjects underwent EEG examination during brushing stimulation of the right forearm.(More)