- Full text PDF available (1)
- This year (0)
- Last 5 years (2)
- Last 10 years (4)
We studied the effect of prostaglandins on presynaptic NMDA receptors. Prostaglandin E2 inhibited NMDA-induced 45Ca2+ uptake by synaptosomes in low concentrations (IC50 ∼10 µM), but potentiated it in higher concentrations. Prostaglandin D2 increased 45Ca2+ uptake by synaptosomes during stimulation of NMDA receptors. Our results indicate that prostaglandins… (More)
It was demonstrated that uridine affects presynaptic NMDA and kainite receptors of rat brain cortex. Uridine considerably inhibited 45Ca2+ uptake into synaptoneurosomes (IC50=7.1×10−12 M) under conditions NMDA stimulation and increased it under conditions AMPA stimulation (157.8%).
We studied the effect of somatostatin on presinaptic NMDA receptors and postsinaptic GABA, NMDA, and AMPA receptors in rat brain. It was shown that somatostatin inhibits NMDAinduced 45Ca2+ uptake into synaptosomes isolated from rat brain cortex (IC50=2.8×10–11 M). Somatostatin potentiates AMPA receptors and inhibits hippocampal NMDA receptors in the entire… (More)
This chapter contains tutorials for using Map Viewer. Step-by-step instructions are provided for several common biological research problems that can be addressed by exploiting the whole-genome and positional perspectives of Map Viewer. Please be aware that the examples in these tutorials may return different results when you execute them, because the… (More)