Andreas V. M. Herz

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Spike-frequency adaptation is a prominent feature of neural dynamics. Among other mechanisms, various ionic currents modulating spike generation cause this type of neural adaptation. Prominent examples are voltage-gated potassium currents (M-type currents), the interplay of calcium currents and intracellular calcium dynamics with calcium-gated potassium(More)
The antennal lobe plays a central role for odor processing in insects, as demonstrated by electrophysiological and imaging experiments. Here we analyze the detailed temporal evolution of glomerular activity patterns in the antennal lobe of honeybees. We represent these spatiotemporal patterns as trajectories in a multidimensional space, where each dimension(More)
Neurons integrate subthreshold inputs in a frequency-dependent manner. For sinusoidal stimuli, response amplitudes thus vary with stimulus frequency. Neurons in entorhinal cortex show two types of such resonance behavior: stellate cells in layer II exhibit a prominent peak in the resonance profile at stimulus frequencies of 5-16 Hz. Pyramidal cells in layer(More)
The fundamental building block of every nervous system is the single neuron. Understanding how these exquisitely structured elements operate is an integral part of the quest to solve the mysteries of the brain. Quantitative mathematical models have proved to be an indispensable tool in pursuing this goal. We review recent advances and examine how(More)
Sensory systems must translate incoming signals quickly and reliably so that an animal can act successfully in its environment. Even at the level of receptor neurons, however, functional aspects of the sensory encoding process are not yet fully understood. Specifically, this concerns the question how stimulus features and neural response characteristics(More)
Sensory memory is a short-lived persistence of a sensory stimulus in the nervous system, such as iconic memory in the visual system. However, little is known about the mechanisms underlying olfactory sensory memory. We have therefore analyzed the effect of odor stimuli on the first odor-processing network in the honeybee brain, the antennal lobe, which(More)
Animals that rely on acoustic communication to find mates, such as grasshoppers, are astonishingly accurate in recognizing song patterns that are specific to their own species1,2. This raises the question of whether they can also solve a far more complicated task that might provide a basis for mate preference and sexual selection: to distinguish individual(More)
Various classes of neurons alternate between high-frequency discharges and silent intervals. This phenomenon is called burst firing. To analyze burst activity in an insect system, grasshopper auditory receptor neurons were recorded in vivo for several distinct stimulus types. The experimental data show that both burst probability and burst characteristics(More)
We investigate the energy efficiency of signaling mechanisms that transfer information by means of discrete stochastic events, such as the opening or closing of an ion channel. Using a simple model for the generation of graded electrical signals by sodium and potassium channels, we find optimum numbers of channels that maximize energy efficiency. The optima(More)
Despite intrinsic noise sources, neurons can generate action potentials with remarkable reliability. This reliability is influenced by the characteristics of sensory or synaptic inputs, such as stimulus frequency. Here we use conductance-based models to study the frequency dependence of reliability in terms of the underlying single-cell properties. We are(More)