Andreas U. Wali

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BACKGROUND Recent trials have demonstrated an association between high activated partial thromboplastin time (aPTT) and bleeding, intracranial hemorrhage, reinfarction, and death in patients with acute coronary syndromes treated with heparin. Of all the factors that affect aPTT in patients treated with heparin, body weight is most strongly correlated. (More)
To the Editor: The recent publication by Unno et al concluded that adiponectin is an indicator of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy. There are some points to be concerned before using this conclusion. First, only 26 cases were investigated in this work and this might be a weakness in statistical analysis.(More)
Context: Unfractionated heparin remains widely utilized in the treatment of acute coronary syndromes (ACS). However, limited data exist on optimal dosing and range of activated partial thromboplastin time (aPTT) in this setting. A large trial of thrombolysis for acute myocardial infarction has reported an association between longer aPTTs and adverse(More)
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