Learn More
OBJECTIVES To compare cardiovascular risk factor levels between non-westernized Melanesians, apparently free from stroke and ischaemic heart disease, nd healthy Swedish populations, and to analyse, among adult Melanesians, relations with age, sex and smoking status. DESIGN Cross-sectional survey. SUBJECTS (i) Traditional horticulturalists in Kitava,(More)
BACKGROUND Raised blood pressure is common in acute stroke, and is associated with an increased risk of poor outcomes. We aimed to examine whether careful blood-pressure lowering treatment with the angiotensin-receptor blocker candesartan is beneficial in patients with acute stroke and raised blood pressure. METHODS Participants in this randomised,(More)
BACKGROUND Riks-Stroke, the Swedish Stroke Register, is the world's longest-running national stroke quality register (established in 1994) and includes all 76 hospitals in Sweden admitting acute stroke patients. The development and maintenance of this sustainable national register is described. METHODS Riks-Stroke includes information on the quality of(More)
BACKGROUND AND PURPOSE Depression after stroke is often described as underdiagnosed and undertreated. However, there are few data on self-reported depression and use of antidepressants in stroke patients at large. MATERIALS AND METHODS In the Swedish national quality assessment register, Riks-Stroke, 15 747 stroke survivors are recorded. They were asked(More)
OBJECTIVE To estimate the prevalence of disabling spasticity (DS) 1 year after first-ever stroke. DESIGN Cross-sectional survey 1 year after first-ever stroke. METHODS Patients above 18 years from one county with first-ever stroke were identified by use of the national stroke registry. A representative sample of 163 patients was created and 140 of these(More)
OBJECTIVES To estimate the excess cost of stroke in Sweden and the potential costs that could be avoided by preventing first-ever strokes. METHODS We adopted the incidence approach for estimating the present value of both direct and indirect costs. Data on mortality, stroke recurrence, and inpatient care were estimated from a national register of patient(More)
OBJECTIVES To investigate the neuroprotective potential of the Src family kinase (SFK) inhibitor 4-amino-5-(4-chlorophenyl)-7-(t-butyl) pyrazolo(3,4-d)pyrimidine (PP2) in transient focal cerebral ischemia in the rat. MATERIAL AND METHODS Sprague-Dawley rats were exposed to transient (90 min) middle cerebral artery occlusion (MCAO) and evaluated after 1(More)
OBJECTIVE To explore the occurrence of, and risk factors for, spasticity until 6 months after first-ever stroke. METHODS Forty-nine patients were examined at day 2-10, at 1 month, and at 6 months. The modified Ashworth Scale was used to assess resistance to passive movements. A comprehensive clinical examination was performed to identify other positive(More)
OBJECTIVES The purpose was to compare the completeness of case ascertainment in two stroke registers, one local population-based, the other a national quality register (Riks-Stroke), and to examine if patient characteristics could be affected by selection bias. MATERIAL AND METHODS By the way of linking and matching computer files, the completeness of(More)
OBJECTIVES To study the impact of blood glucose concentrations on early stroke mortality in diabetic and non-diabetic stroke patients, and to identify the optimal blood glucose concentration for each patient category. MATERIAL AND METHODS A representative sample of 81 diabetic and 366 non-diabetic stroke patients was studied. Logistic regression analyses(More)