Andreas Türler

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Endotoxemia causes an inflammatory response within the intestinal muscularis and gastrointestinal dysmotility. We hypothesize that the resident macrophage-derived chemokine monocyte chemoattractant protein-1 (MCP-1) plays a significant role in the recruitment of leukocytes into the lipopolysaccharide (LPS)-stimulated rat intestinal muscularis. MCP-1 mRNA(More)
BACKGROUND Inflammatory events within the intestinal muscularis, including macrophage activation and leukocyte recruitment, have been demonstrated to participate in causing postoperative ileus. Recently, glycine has gained attention due to its beneficial immunomodulatory effects in transplantation, shock and sepsis. METHODS Muscularis glycine receptors(More)
Terbium-149 is among the most interesting therapeutic nuclides for medical applications. It decays by emission of short-range α-particles (Eα = 3.967 MeV) with a half-life of 4.12 h. The goal of this study was to investigate the anticancer efficacy of a 149Tb-labeled DOTA-folate conjugate (cm09) using folate receptor (FR)-positive cancer cells in vitro and(More)
BACKGROUND Terbium has attracted the attention of researchers and physicians due to the existence of four medically interesting radionuclides, potentially useful for SPECT and PET imaging, as well as for α- and β(-)-radionuclide therapy. The aim of this study was to produce (152)Tb (T 1/2 = 17.5 h, Eβ+av = 1140 keV) and evaluate it in a preclinical setting(More)
BACKGROUND Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) rank among the most frequently applied bariatric procedures worldwide due to their positive risk/benefit correlation. A systematic review revealed a similar excess weight loss (EWL) 2 years postoperatively between SG and RYGB. However, there is a lack of randomized controlled(More)
The unambiguous identification of new superheavy elements (SHE) is a very difficult task for both, physicists and chemists due to very low production rates, absence of a link to known isotopes, and unknown chemical, and decay properties. Chemical studies of SHE are of great importance because they can identify the proton number of the studied isotopes.(More)
During the TASCA commissioning phase competitive tests of two types of focal plane detectors for TASCA – a Position Sensitive Silicon Stripe Detector (PSSSD) and a Double Sided Silicon Strip Detector (DSSSD)-have been performed. The DSSSD proved to be more reliable and more sensitive for the detection of decay chains due to the high granularity of the(More)
  • Ch E Düllmann, W Brüchle, R Dressler, K Eberhardt, B Eichler, R Eichler +28 others
  • 2002
The periodic table provides a classification of the chemical properties of the elements. But for the heaviest elements, the transactinides, this role of the periodic table reaches its limits because increasingly strong relativistic effects on the valence electron shells can induce deviations from known trends in chemical properties. In the case of the first(More)
  • E Strub, J V Kratz, A Kronenberg, A Nähler, P Thörle, Universität Mainz +14 others
  • 2001
The distribution coefficient (K d) of 261 Rf on ion exchange resins at various HNO 3 /HF concentrations had been studied [1]. Rf was eluted at higher HF concentrations from CIX than Zr and Hf and rather resembled Th. Up to 1 M HF, Rf was not retained on the AIX also resembling its pseudo-homolog Th. Th is known to form no anionic fluoride complexes, while(More)