Andreas Schöbel

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The anterior cingulate cortex (ACC) represents a phylogenetically ancient region of the mammalian brain that has undergone recent adaptive changes in humans. It contains a large spindle-shaped cell type, referred to as von Economo neuron (VEN) that has been shown to be involved in the pathophysiology of various neuropsychiatric disorders. Schizophrenia is a(More)
We analyzed the effect of dexamethasone on gram-negative bacteria derived lipopolysaccharide (LPS) induced inflammation in astroglial/microglial co-cultures. At the cellular level the microglial phenotype converted to an activated type after LPS incubation. Furthermore, LPS compromised functional astroglial properties like membrane resting potential,(More)
Suicide is the most important incident in psychiatric disorders. Psychological pain and empathy to pain involves a neural network that involves the anterior cingulate cortex (ACC) and the anterior insula (AI). At the neuronal level, little is known about how complex emotions such as shame, guilt, self-derogation and social isolation, all of which feature(More)
The design of new railway infrastructure is a complex planning process today in most Eu-ropean countries due to several requirements. From an operational point of view new infrastructure basically has to fulfil the requirements defined by the later customers who are the railway undertakings. Hereby passenger traffic is often organised in a periodic(More)
The design of new railway infrastructure is a complex planning process today in most European countries due to several requirements. From an operational point of view new infrastructure basically has to fulfil the requirements defined by the later customers who are the railway undertakings. Hereby passenger traffic is often organised in a periodic timetable(More)
SUMMARY The introduction of the new ÖBB management operation system has to result in an increase in reliability and quality. At the same time, operational costs are to be reduced. These goals can only be achieved by concentrating the responsible staff on a few locations. Consequently, the traditional train supervision has to be replaced by a technical(More)
This paper evaluates the effectiveness of reducing scheduled station dwell time to save energy on commuter rail lines. Most commuter rail schedules include a fixed amount of dwell time (e.g. 30-seconds) at each station. For stations with higher demand the station dwell time may be up to 1 minute. Generally the station dwell time is set high enough to meet(More)
Due to the ongoing remote control in signalling technology train observation by employees is reduced at traditional locations e.g. place of a station manager. The Austrian Federal Railways (ÖBB) Infrastructure Operation Company has recognised this trend very early. Several years ago, they started the construction of a wayside detection system to control the(More)