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Protein kinase A (PKA) is a ubiquitous kinase that phos-phorylates a broad variety of substrates. A-kinase anchoring proteins (AKAPs) confer specificity to PKA signaling by tethering the kinase to distinct cellular compartments, thereby limiting the access of PKA to a defined pool of its substrates. [1] Interactions between AKAPs and PKA play key roles in a(More)
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